在这部七日生剧情/犯罪片中,一次掩护邱永邦抽老千的行为，将李晓宇平静的生活打破。赌场老板被害，李晓宇被当成最大嫌犯逮捕，身为平面模特的女友文文在此时被霍雷兹帮的人贩子盯上绑走。一时无法脱身的李晓宇请邱永邦帮忙找回文文，却不知道，绑走文文的人正是邱永邦一伙。
知道真相后的李晓宇以警察线人的身份追上邱永邦所在的华人旅游大巴，大巴已被邱永邦一伙劫持。为了找回文文，也为了拯救一车华人同胞，李晓宇不顾邱永邦劝阻，坚定地留在大巴上。
外科医生简妮为了给母亲报仇，跟踪生父洪银河上了大巴。机智勇敢的简妮成为李晓宇最好的搭档，两人戮力同心，救下一车人质并找回文文，邱永邦无奈受控于霍雷兹帮的原因也浮出水面。邱永邦得到了李晓宇的谅解，兄弟齐心，共赴美墨边境，最终协助警方捣毁霍雷兹帮，救出更多无辜之人。经历七日生死之旅后，千疮百孔的兄弟情、父女情都得到了救赎。
Li Xiaoyu was a Chinese veteran. He lived in the US and found a job to be a casino player. Wenwen was her girlfriend. She was deceived by a human trafficking organization and then kidnapped by them. Qiu Yongbang was Li's friend. He was a member of a gang. He was controlled by the gang so he couldn't leave the gang unless he make up his mistakes. He seemed to be connected with the kidnapping of Wenwen. But while they were searching for her, they were arrested by the cops. The only way for Li to find Wenwen was to be an asset of the police.
这电视剧调色好像电影哇——烂剧无疑！。买收视率买水军买涨分被曝光，还删随便帖子，真无耻！。插刀教四大护法之一主演的烂剧。原以为是广播剧出了电视剧版 结果大失所望。看豆瓣很多年，第一次忍不住评分。创新的勇气可嘉，细节还需努力。电影化的叙事。节奏快 悬念多。为了评价，我专门下载了豆瓣。《七日生》我的神剧，为什么还不公布此剧的评分啊？。
