在这部怪物大追緝恐怖片中,從實驗室逃出的殺人怪物在小鎮大開殺戒… FBI探員妮可回到家鄉奧羅尼格洛協助處理一連串離奇的謀殺案。當地警長謝里夫對於上層派女人協助辦案感到羞辱和不悅。起初他們覺得這是走私者或毒販隨機的殺人行動，直到他們發現一具血被抽乾的屍體，才開始思考不同的可能性。此時一位神秘女子和 她的助手在驗屍的過程中出現，表示她們研究的沙漠作戰怪物物逃脫了，才會導致這一連串駭人事件，她們請求妮可協助她們抓回這殺人怪物，於是特別小組要來追捕這軍事惡魔！
After being cleared in an internal investigation F.B.I. special agent Nicole Diaz is reinstated and sent back home to the town of Oro Negro to help solve several bizarre murders of two agents in Sarasota Fl. She's met with disdain by the local Sheriff, a good old boy who doesn't believe they are being taken seriously and is insulted they sent a woman. At first, it's thought the killings are random acts committed by smugglers or drug dealers that is, until the resident Tribal Ranger realizes the bodies have been drained of blood and suspects it is something more but his beliefs are dismissed. Soon after a mysterious woman and her aide appear during an autopsy and claim responsibility for creating the perfect killing machine. A creature designed specifically for desert warfare to be used by the military. However, it has escaped and they need help reacquiring it. Unsure who to believe or trust, Nicole assembles a team and they set out to capture it but bizarre events makes her second ...
