在这部精灵俏女巫动画片中,表面看来，江藤兰世（原荣里子 配音）只是一个普普通通的女孩子，可实际上，她出生在一个不得了的家庭之中。兰世的父亲望里（安原义人 配音）是一名吸血鬼，而母亲椎罗（小原乃梨子 配音）拥有着狼人的血统，这也就意味着，兰世既有可能继承父亲的血统成为一名吸血鬼，也可能成为狼女。只是血统的差异至今还没有在兰世的身上显现出来。
兰世终于能够上学啦，在学校里，兰世遇见了名为真壁俊（水岛裕 配音）的男生，情窦初开的她瞬间坠入了情网。哪知道同班女生神谷曜子（富永美衣奈 配音）也一直暗恋着真壁俊，两个女生之间产生了激烈的竞争，兰世的特异能力亦在矛盾之中被激发了出来。
Ranze Etou is a very special girl: her mother is a werewolf, her father is a vampire and she herself has the ability to shapeshift. In spite of all this, she strives to lead the life of an ordinary human schoolgirl. Her one ambition is to get with the young handsome athlete Shun Makabe, which is complicated by the fact that all supernatural creatures must keep their identity hidden from the human world. To make matters worse, another girl, a gangster's daughter named Yoko Kamiya, is trying to claim Shun for herself. Will Ranze ever manage to get with Shun?
