在这部达芬奇大冒险：拯救蒙娜丽莎动画/家庭/冒险片中,达芬奇生活在一个宁静和平的小村庄里，每天都沉迷在自己研究的神奇发明中。他有个名叫洛伦佐的好朋友，勤劳勇敢，喜欢自然，总是给达芬奇许多帮助。达芬奇喜欢一名叫“蒙娜丽莎”的聪慧又机敏的女孩，在他们身边总是会发生许多有趣的事儿。直到一场大火烧毁了蒙娜丽莎家的农田，她的父亲为了生计，不得不让蒙娜丽莎嫁给一个富有却惹人讨厌的家伙。为了解救自己的伙伴，达芬奇从一个神秘说书人那里听说在弗洛伦撒附近的海域内藏有宝藏。
于是达芬奇与小伙伴们踏上了冒险的旅程，但等待他们的却是海盗们设下的重重圈套……
In the late Middle Age's Italy, Leonardo "Leo" Da Vinci is a young boy lover to invent advanced machines who lives happy with his best friend Lorenzo and beauty Lisa, being secretly fall in love with her. After to test the first dive suit of his creation in a lake, tragedy appears when coming back to home Lisa realizes that her house and lands have been burned by a fire. Owner of the lands threats Lisa's father to marry her with his son if he doesn't give all money he debts as retribution by the fire, causing Lisa's sorrow. Trying to save her, Leo Da Vinci decides travel to Florencia to gain money and pay the debt with help of Lorenzo. Unable to keep the secret, Lorenzo reveals Lisa Leo's plans, and Lisa joins her friends to make the travel to the big city, where they meet a storyteller that explains in a plaza the story of a pirate ship sunken with a great treasure inside it. Believing it as a true event, Leo buys the treasure map to the storyteller, but it's stolen by a rogue and ...
